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New study to monitor COVID-19 illness and vaccine safety, effectiveness in children and youth in Canada

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MONTREAL, June 11, 2021 (GLOBE NEWSWIRE) — The Authorities of Canada, by its COVID-19 Immunity Job Pressure (CITF) and Vaccine Surveillance Reference Group (VSRG), is supporting a brand new pan-Canadian examine that may monitor the results of sickness from COVID-19, in addition to the protection and effectiveness of COVID-19 vaccines in kids and youth. Roughly $1.8 million is being invested on this analysis undertaking.

The vaccines being administered to protect in opposition to COVID-19 have gone by rigorous security and efficacy evaluations in all eligible age teams. Continued surveillance for any vaccine is a crucial part of guaranteeing the protection and effectiveness of all vaccines for the overall inhabitants. This analysis examine is complemented by ongoing security monitoring by the Public Well being Company of Canada, Well being Canada, and a number of public well being organizations.

“Our examine will monitor most pediatric hospital visits in Canada and can goal to establish these that could be related to a COVID-19 an infection or vaccination,” says Dr. Karina High, a principal investigator on the examine and a lead investigator on the Canadian Middle for Vaccinology at Dalhousie College and the IWK in Halifax. “We need to monitor the signs of any kids or adolescents admitted to hospital because of COVID-19, together with for multisystem inflammatory syndrome in kids (MIS-C), in addition to observe the continued security and effectiveness of COVID-19 vaccines, as we transfer towards a return to regular life.”

The examine can be carried out by Canada’s IMPACT (Immunization Monitoring Program ACTive) community, which has been repeatedly monitoring a number of pediatric vaccines for greater than 30 years. Its efforts inform public well being and medical consultants of surprising post-vaccine occasions. The IMPACT community captures about 90 per cent of tertiary pediatric hospital admissions in Canada and is properly positioned to judge the influence of vaccination packages on circumstances of COVID-19 in kids and youth who’re in hospital.

“As COVID-19 vaccines are made out there to 12- to 17-year-olds, and doubtlessly youthful age teams sooner or later, our staff will work to make sure continued vaccine effectiveness by finding out whether or not vaccination is related to fewer kids and youth being admitted to hospital with COVID-19, and fewer extreme circumstances of illness,” explains Dr. Shaun Morris, a principal investigator on the examine and a pediatric infectious illness doctor at The Hospital for Sick Kids (SickKids) in Toronto. “This examine, which started on June 1, will construct upon the data gathered in our analysis staff’s Canadian Paediatric Surveillance Program COVID-19 Research (CPSP COVID-19 Study). That examine collected knowledge on this sickness from the start of the pandemic till the top of Could 2021, to offer a extra full understanding of how COVID-19 impacts kids and youth and the way we are able to finest shield them.”  

“With the vaccine rollout in youth ages 12 to 17 already underway in Canada, this examine is extraordinarily related,” says Dr. Caroline Quach Thanh, VSRG Co-Chair and Medical Lead in An infection Prevention and Management on the CHU Sainte-Justine, the place she works as a pediatric infectious illness guide and a medical microbiologist. “This examine will carry collectively info from hospitals throughout Canada, to extra rapidly establish patterns of expertise that may assist decide whether or not a number of the issues that they’re seeing are associated to vaccination. The sooner our consultants are in a position to react, the sooner we will discover options.”

“Kids and youth have made lots of sacrifices to assist scale back the unfold of COVID-19,” says Canada’s Chief Public Well being Officer Dr. Theresa Tam. “These research on the results of sickness from COVID-19, and COVID-19 vaccine security and effectiveness will assist us study extra about the perfect methods to guard youthful Canadians and their households. Monitoring security and effectiveness of COVID-19 vaccines on this inhabitants may also contribute to optimum COVID-19 prevention and management, inhabitants huge.”

In regards to the Canadian Immunization Monitoring Program ACTive (IMPACT)

The Canadian Immunization Monitoring Program ACTive (IMPACT) is funded by the Public Well being Company of Canada (PHAC) in collaboration with the Canadian Paediatric Society (CPS) to conduct hospital-based sentinel surveillance for vaccine-preventable illnesses and choose opposed occasions following immunization (AEFIs) resulting in hospitalization at 12 pediatric tertiary care centres from Vancouver, BC to St John’s, NL which seize roughly 90 per cent of tertiary care pediatric beds in Canada and about 50 per cent of pediatric hospitalizations.

In regards to the Vaccine Surveillance Reference Group

The Vaccine Surveillance Reference Group (VSRG) helps the monitoring of the protection and effectiveness of COVID-19 vaccines in Canada. It’s a consortium of Canadian organizations —the Public Well being Company of Canada (PHAC), the Canadian Analysis Immunization Community (CIRN), the Nationwide Advisory Committee on Immunization (NACI), and the COVID-19 Immunity Job Pressure (CITF)— working collaboratively to pool experience on vaccine surveillance. The VSRG experiences to PHAC and is supported by the CITF Secretariat. It’s co-chaired by the leaders of NACI and CIRN. Amongst its obligations, the VSRG, by the CITF Govt Committee, makes suggestions to PHAC on funding analysis groups that may deal with vital points of the immune response, security, and effectiveness of COVID-19 vaccines with public well being relevance and with consideration to all precedence teams. For extra info go to: https://www.covid19immunitytaskforce.ca/vaccine-surveillance-reference-group-vsrg/

In regards to the COVID-19 Immunity Job Pressure

The Authorities of Canada established the COVID-19 Immunity Job Pressure in late April 2020. The Job Pressure is overseen by a Management Group of volunteers that features main Canadian scientists and consultants from universities and healthcare amenities throughout Canada who’re centered on understanding the character of immunity arising from the novel coronavirus that causes COVID-19. To that finish, the CITF is supporting quite a few research to find out the extent of SARS-CoV-2 an infection in Canada (within the normal inhabitants in addition to in particular communities and precedence populations), perceive the character of immunity following an infection, develop improved antibody testing strategies, and assist monitor the effectiveness and security of vaccines as they’re rolled out throughout Canada. The Job Pressure and its Secretariat work intently with a variety of companions, together with governments, public well being companies, establishments, well being organizations, analysis groups, different job forces, and engages communities and stakeholders. Most lately, the Job Pressure has been requested to help vaccine surveillance, effectiveness and security as a part of its total goal to generate knowledge and concepts that inform interventions aimed toward slowing—and in the end stopping—the unfold of SARS-CoV-2 in Canada. For extra info go to: https://www.covid19immunitytaskforce.ca

Media contacts

IMPACT
Gen Brouillette
genevieveb@cps.ca
+1.613.526.9397 ext. 247

COVID-19 Immunity Job Pressure/Vaccine Surveillance Reference Group
media@covid19immunitytaskforce.ca

Rebecca Burns
Cell: +1.438.871.8763
Caroline Phaneuf
Cell: +1.514.444.4532

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